Pharmaron

Graduate Scientist role supporting LC-MS/MS bioanalysis, DMPK, ADME and biotransformation studies through laboratory analysis, method development, data interpretation, and scientific reporting.Pharmaron is a global CRO helping pharma and biotech companies bring new therapies to life. With over 25,000 employees worldwide across 23 locations in the US, UK and China, we support drug discovery through to manufacturing with fully integrated, high-quality services.We are currently seeking a Scientist to join our growing Discovery Bioanalysis and Biotransformation team in Hoddesdon. This is an exciting opportunity for an ambitious early-career scientist looking to build expertise in LC-MS/MS bioanalysis within a dynamic drug discovery environment.The role would suit a recent graduate who has ideally completed an industrial placement, a candidate with postgraduate research experience involving LC-MS, or someone with up to a few years of industry experience in bioanalysis, DMPK, ADME or a related analytical laboratory setting.Working as part of a collaborative and highly experienced team, you will gain exposure to a broad range of discovery-stage studies, supporting bioanalysis, DMPK and biotransformation projects for pharmaceutical and biotechnology clients worldwide.Unlike larger organisations where these activities may sit across multiple specialist departments, this role offers the opportunity to gain experience across several scientific disciplines, helping accelerate your technical development and career progression. Key Roles and Responsibilities:Perform LC-MS/MS-based bioanalysis to support discovery bioanalysis, DMPK and biotransformation studies. Prepare and analyse samples generated from in vitro and in vivo studies. Support the development, optimisation and qualification of analytical methods for small molecules, peptides and related compounds. Generate, review and interpret analytical data, ensuring high levels of accuracy and data quality. Support fast-paced project delivery through effective laboratory planning and execution. Contribute to troubleshooting analytical challenges under the guidance of senior team members. Collaborate with scientists across Discovery DMPK Maintain accurate experimental records and contribute to scientific reporting. Follow laboratory procedures, safety requirements and quality standards. Continue developing technical expertise through practical experience, training and mentorship within the team.Essential Requirements:BSc or MSc in Chemistry, Biochemistry, Pharmacology, Biological Sciences or another relevant scientific discipline. Industrial placement experience, postgraduate research experience, or up to approximately 3 years of relevant laboratory experience. Exposure to analytical chemistry equipment inclduing LC-MS or LC-MS/MS through industry, academic research or industrial placement projects. Strong practical laboratory skills and an interest in analytical science and drug discovery. Excellent attention to detail and commitment to producing high-quality scientific data. Good organisational skills and ability to manage multiple priorities effectively. Strong written and verbal communication skills. Ability to work collaboratively within a team whilst also taking ownership of individual tasks. Enthusiastic, proactive and keen to develop new technical skills. Desirable experience: While not essential, experience in one or more of the following areas would be advantageous:Discovery bioanalysis, DMPK, ADME or biotransformation studies.Operation of LC-MS/MS instrumentation, including triple quadrupole systems and/or QTOFs.Sample preparation and extraction techniques for biological matrices.Data analysis software associated with LC-MS platforms (e.g. Analyst, Sciex OS, MultiQuant).Pharmacokinetic concepts and interpretation of PK data.Experience working within a CRO, pharmaceutical or biotechnology environment.Exposure to high-throughput laboratory workflows.Python, R or other data analysis tools for scientific applications. Our CompanyPharmaron is a trusted partner to many of the world's leading pharmaceutical and biotechnology companies, delivering high-quality scientific solutions across the drug discovery and development pathway.Our Hoddesdon site provides modern laboratory facilities and a collaborative scientific environment supporting Discovery, Analytical Sciences, Process Chemistry and Product Development activities. Why Join Pharmaron?Gain hands-on experience using LC-MS/MS within a leading drug discovery environment.Develop expertise across bioanalysis, DMPK, ADME and biotransformation studies.Work on diverse and scientifically challenging projects for global pharmaceutical and biotech clients.Learn from experienced scientists within a supportive and collaborative team.Access ongoing training and development opportunities to support your career growth.Be part of a company that plays a direct role in advancing innovative new medicines for patients worldwide.

Posted 2 days ago

A laboratory-based Scientist role supporting drug discovery by conducting in vitro DMPK/ADME experiments, analysing results, and working with multidisciplinary scientific teams.Pharmaron is a global CRO helping pharma and biotech companies bring new therapies to life. With over 21,000 employees worldwide across 23 locations in the US, UK and China, we support drug discovery through to manufacturing with fully integrated, high-quality services.We’re proud of the impact we make and just last year, we supported over 780 discovery projects, 1,000+ CMC programmes, and 1,000+ clinical trials across all phases. Our teams are involved in everything from small molecules to biologics and gene therapies, and we work with more than 3,000 global customers. About the RoleWe are looking for Scientist to join our In Vitro DMPK Assay group at our Hoddesdon site supporting Discovery ADME screening through to early development (e.g. studies associated with ICHM12). In this role you will be working with others to create in vitro DMPK laboratory solutions to enable projects, ensuring appropriate experimental methods are followed.Key ResponsibilitiesFollow and understand in vitro DMPK laboratory methods to answer project questions. Effectively work as part of multi-disciplinary teams to deliver agreed project requirements. Work with others to contribute with data and laboratory skills under the guidance, supervision and mentorship of others.Report and document results of experiments in line with department practices and governing policies, including reporting to support IND applications.Act as a system owner of equipment and instrumentation if required Implement and adoption of key internal business practices and applicable external regulations (e.g. Human Tissue Act), and adhere to all policies governing business activities. Support and positively contribute to departmental or site audits as directed by scientific supervisor / Line Manager as necessary. Candidate ProfileEssential:MSc or BSc in Biochemistry, Biology or relevant subject Practical laboratory experience gained during your studies or an industrial placement is desirableProven ability to collaborate effectively in multi-disciplinary scientific teams.Excellent verbal and written communication skills.Excellent interpersonal skills with the ability to build strong working relationships with stakeholders and customers Desirable:Understanding of enzyme kineticsExperience of liquid handling systemsCell culture skills, including both immortalised and primary cellsUnderstanding of physicochemical properties of moleculesMolecular Biology SkillsWhy Pharmaron?Collaborative Culture: Thrive in our inclusive and collaborative environment, where teamwork and innovation go hand in hand. Here, your voice matters, and your contributions make a real impact. "Employees Number One" and "Clients Centered" are the core cultural values at Pharmaron. Our culture, which sets Pharmaron apart from other organizations, has evolved from our deep commitment to our employees, partners and collaborators.

Posted 5 days ago